Hayato Iwase Selected Research

Heterologous Transplantation (Xenotransplantation)

1/2021	Pig kidney xenotransplantation: Progress toward clinical trials.
1/2021	The Role of Interleukin-6 (IL-6) in the Systemic Inflammatory Response in Xenograft Recipients and in Pig Kidney Xenograft Failure.
1/2021	A perspective on the potential detrimental role of inflammation in pig orthotopic heart xenotransplantation.
11/2020	The immune system in infants: Relevance to xenotransplantation.
10/2019	Indicators of impending pig kidney and heart xenograft failure: Relevance to clinical organ xenotransplantation - Review article.
1/2019	Incidence of Neoplasia in Pigs and Its Relevance to Clinical Organ Xenotransplantation.
1/2019	Evidence for the important role of inflammation in xenotransplantation.
1/2019	Will donor-derived neoplasia be problematic after clinical pig organ or cell xenotransplantation?
1/2019	Chronic dialysis in patients with end-stage renal disease: Relevance to kidney xenotransplantation.
11/2018	Skin xenotransplantation: Historical review and clinical potential.

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Hayato Iwase Research Topics

Disease

9	Inflammation (Inflammations) 01/2021 - 01/2015
7	Thrombocytopenia (Thrombopenia) 10/2019 - 11/2011
6	Infections 01/2021 - 05/2015
2	Thrombosis (Thrombus) 10/2019 - 05/2014
2	Lymphoproliferative Disorders (Lymphoproliferative Disorder) 01/2019 - 01/2019
2	Neoplasms (Cancer) 01/2019 - 01/2019
2	Proteinuria 10/2018 - 11/2015
2	Thrombotic Microangiopathies 01/2018 - 05/2015
1	Cytokine Release Syndrome 07/2022
1	Sickle Cell Anemia (Hemoglobin S Disease) 11/2021
1	Anemia 01/2021
1	Hypertrophy 01/2021
1	Hypovolemia 01/2021
1	Hypoplastic Left Heart Syndrome 11/2020
1	Congenital Heart Defects (Congenital Heart Defect) 11/2020
1	Vasculitis (Vasculitides) 10/2019
1	Frailty 01/2019
1	Chronic Kidney Failure (Chronic Renal Failure) 01/2019
1	Burns 11/2018
1	Renal Insufficiency (Renal Failure) 10/2018
1	Hypoalbuminemia 10/2018
1	Wounds and Injuries (Trauma) 10/2017
1	Brain Death (Brain Dead) 01/2016
1	Disease Progression 01/2016
1	Shock 05/2015

Drug/Important Bio-Agent (IBA)

5	Fibrinogen (Factor I)FDA Link 10/2019 - 05/2015
3	Proteins (Proteins, Gene)FDA Link 01/2017 - 07/2015
2	Interleukin-6 (Interleukin 6)IBA 07/2022 - 01/2021
2	Anti-Inflammatory Agents (Anti-Inflammatories)IBA 01/2021 - 01/2019
1	Etanercept (Enbrel)FDA Link 01/2021
1	AntibodiesIBA 11/2020
1	AntigensIBA 11/2020
1	CarbohydratesIBA 11/2020
1	Interleukin-6 Receptors (Interleukin 6 Receptor)IBA 01/2020
1	InterleukinsIBA 01/2020
1	Intravenous Immunoglobulins (IVIG)FDA Link 01/2020
1	CalciumIBA 10/2018
1	SolutionsIBA 10/2018
1	Growth Hormone (Somatotropin)IBA 10/2018
1	ElectrolytesIBA 10/2018
1	CreatinineIBA 10/2018
1	Phosphates (Orthophosphate)IBA 10/2018
1	Erythropoietin FDA Link 10/2018
1	Erythropoietin Receptors (Erythropoietin Receptor)IBA 10/2018
1	Complement System Proteins (Complement)IBA 01/2018
1	Histones (Histone)IBA 10/2017
1	Interleukin-17 (Interleukin 17)IBA 01/2017
1	Insulin (Novolin)FDA Link 01/2016
1	Blood Glucose (Blood Sugar)IBA 01/2016
1	Triiodothyronine (Liothyronine)FDA LinkGeneric 01/2016
1	O-(glucuronic acid 2- sulfate)- (1- - 4)- O- (2,5)- anhydromannitol 6-sulfateIBA 01/2016
1	fibrin fragment D (D-dimer)IBA 09/2015
1	C-Reactive ProteinIBA 09/2015
1	Endothelial Protein C ReceptorIBA 05/2014
1	ThrombomodulinIBA 05/2014
1	lipoprotein-associated coagulation inhibitor (TFPI)IBA 05/2014

Therapy/Procedure

15	Heterologous Transplantation (Xenotransplantation) 01/2021 - 11/2011
7	Transplantation 01/2021 - 09/2015
3	Therapeutics 01/2021 - 11/2011
1	Blood Transfusion (Blood Transfusions) 11/2021
1	Immunomodulation 01/2019
1	Bone Marrow Transplantation (Transplantation, Bone Marrow) 01/2019
1	Kidney Transplantation 12/2018
1	Euthanasia (Mercy Killing) 12/2018
1	Operative Surgical Procedures 01/2016
1	Cardiopulmonary Bypass (Heart-Lung Bypass) 01/2016
1	Heart Transplantation (Grafting, Heart) 09/2015
1	Catheters 05/2015